SMARCA2

SMARCA2
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2DAT, 5DKC, 4QY4
Identifiers
Aliases	SMARCA2, BAF190, BRM, NCBRS, SNF2, SNF2L2, SNF2LA, SWI2, Sth1p, hBRM, hSNF2a, SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2, BIS
External IDs	OMIM: 600014; MGI: 99603; HomoloGene: 2308; GeneCards: SMARCA2; OMA:SMARCA2 - orthologs
Gene location (Human)
Chr.	Chromosome 9 (human)
End	2,193,624 bp
Gene location (Mouse)
Chr.	Chromosome 19 (mouse)
End	26,755,722 bp
RNA expression pattern
	Top expressed in
	Achilles tendon; ; epithelium of colon; ; left ovary; ; ventricular zone; ; sural nerve; ; right ovary; ; secondary oocyte; ; olfactory zone of nasal mucosa; ; germinal epithelium; ; epithelium of nasopharynx;
	Top expressed in
	neural layer of retina; ; lateral septal nucleus; ; cingulate gyrus; ; dentate gyrus of hippocampal formation granule cell; ; dorsomedial hypothalamic nucleus; ; cerebellar cortex; ; superior frontal gyrus; ; genital tubercle; ; lobe of cerebellum; ; cerebellar vermis;
	More reference expression data
	; ; ; ;
	More reference expression data
Gene ontology
Molecular function	nucleotide binding; transcription coactivator activity; DNA binding; ATP-dependent activity, acting on DNA; helicase activity; histone binding; chromatin binding; hydrolase activity, acting on acid anhydrides; protein binding; hydrolase activity; ATP binding; ATPase activity;
Cellular component	nBAF complex; intracellular membrane-bounded organelle; nucleoplasm; npBAF complex; intermediate filament cytoskeleton; nucleus; SWI/SNF complex;
Biological process	chromatin remodeling; regulation of transcription, DNA-templated; regulation of transcription by RNA polymerase II; negative regulation of transcription by RNA polymerase II; transcription, DNA-templated; nervous system development; positive regulation of transcription, DNA-templated; negative regulation of cell growth; spermatid development; negative regulation of transcription, DNA-templated; positive regulation of transcription by RNA polymerase II; negative regulation of cell population proliferation; transcription by RNA polymerase II;
	Sources:Amigo / QuickGO
Orthologs
	6595
	67155
	ENSG00000080503
	ENSMUSG00000024921
	P51531
	Q6DIC0
NM_139045; NM_001289396; NM_001289397; NM_001289398; NM_001289399;
	NM_001289400; NM_003070
	NM_011416; NM_026003; NM_001347439
NP_001276325; NP_001276326; NP_001276327; NP_001276328; NP_001276329;
	NP_003061; NP_620614
NP_001334368; NP_035546; NP_080279; NP_001392059; NP_001392060;
	NP_001392061; NP_001392062; NP_001392063; NP_001392064; NP_001392065
	Wikidata
View/Edit Human	View/Edit Mouse

Probable global transcription activator SNF2L2 is a protein that in humans is encoded by the SMARCA2 gene.