Sodium-dependent phosphate transport protein 2A

SLC34A1
Identifiers
Aliases	SLC34A1, NPT2, NPTIIa, solute carrier family 34 member 1, NaPi-2a, HCINF2, SLC17A2, SLC11, NAPI-3, FRTS2, NPHLOP1
External IDs	OMIM: 182309; MGI: 1345284; HomoloGene: 20663; GeneCards: SLC34A1; OMA:SLC34A1 - orthologs
Gene location (Human)
Chr.	Chromosome 5 (human)
End	177,398,848 bp
Gene location (Mouse)
Chr.	Chromosome 13 (mouse)
End	55,563,405 bp
RNA expression pattern
	Top expressed in
	kidney tubule; ; metanephric glomerulus; ; renal medulla; ; right lobe of liver; ; human kidney; ; granulocyte; ; blood; ; mucosa of esophagus; ; tonsil; ; zone of skin;
	Top expressed in
	right kidney; ; human kidney; ; proximal tubule; ; clavicle; ; membranous bone; ; maxilla; ; mandible; ; lumbar subsegment of spinal cord; ; rib; ; primary visual cortex;
	More reference expression data
	n/a
Gene ontology
Molecular function	protein homodimerization activity; protein binding; symporter activity; sodium:phosphate symporter activity; PDZ domain binding; protein-containing complex binding;
Cellular component	integral component of membrane; endosome; membrane; intrinsic component of plasma membrane; integral component of plasma membrane; cell surface; brush border membrane; perinuclear region of cytoplasm; membrane raft; vesicle; brush border; cytoplasm; plasma membrane; apical plasma membrane; nuclear speck; mitotic spindle;
Biological process	phosphate ion transport; response to potassium ion; response to estradiol; cellular response to staurosporine; glycoprotein metabolic process; response to cadmium ion; ossification; sodium-dependent phosphate transport; positive regulation of phosphate transmembrane transport; kidney development; response to nutrient; sodium ion transport; response to thyroid hormone; response to peptide hormone; phosphate ion homeostasis; response to magnesium ion; dentinogenesis; response to peptide; response to vitamin A; indole metabolic process; cellular response to metal ion; response to parathyroid hormone; response to lead ion; tricarboxylic acid metabolic process; gentamycin metabolic process; response to growth hormone; arsenate ion transmembrane transport; response to mercury ion; cellular response to parathyroid hormone stimulus; positive regulation of sodium-dependent phosphate transport; positive regulation of membrane potential; protein homooligomerization; cellular phosphate ion homeostasis; sodium ion transmembrane transport; ion transport; phosphate ion transmembrane transport; sodium ion import across plasma membrane;
	Sources:Amigo / QuickGO
Orthologs
	6569
	20505
	ENSG00000131183
	ENSMUSG00000021490
	Q06495; Q7Z725
	Q60825; Q9D2V6
	NM_001167579; NM_003052
	NM_011392
	NP_001161051; NP_003043; NP_003043.3
	NP_035522
	Wikidata
View/Edit Human	View/Edit Mouse

Sodium-dependent phosphate transport protein 2A, also known as Na⁺-P_i cotransporter 2a (NaPi-2a), is a protein in humans that is encoded by the SLC34A1 gene. This gene encodes a member of the type II sodium-phosphate cotransporter family.