Semaphorin-3A

SEMA3A
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1Q47, 4GZ8, 4GZA
Identifiers
Aliases	SEMA3A, COLL1, HH16, Hsema-I, Hsema-III, SEMA1, SEMAD, SEMAIII, SEMAL, SemD, coll-1, semaphorin 3A
External IDs	OMIM: 603961; MGI: 107558; HomoloGene: 31358; GeneCards: SEMA3A; OMA:SEMA3A - orthologs
Gene location (Human)
Chr.	Chromosome 7 (human)
End	84,492,724 bp
Gene location (Mouse)
Chr.	Chromosome 5 (mouse)
End	13,652,533 bp
RNA expression pattern
	Top expressed in
	stromal cell of endometrium; ; epithelium of colon; ; cartilage tissue; ; ventricular zone; ; ganglionic eminence; ; muscle layer of sigmoid colon; ; gonad; ; testicle; ; sural nerve; ; gastric mucosa;
	Top expressed in
	outer enamel epithelium; ; medial vestibular nucleus; ; cervical loop; ; genital tubercle; ; lumbar subsegment of spinal cord; ; fossa; ; left lung lobe; ; epithelium of lens; ; tail of embryo; ; olfactory tubercle;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	chemorepellent activity; semaphorin receptor binding; neuropilin binding;
Cellular component	extracellular region; dendrite; extracellular space; axon; integral component of plasma membrane;
Biological process	sympathetic ganglion development; negative regulation of axon extension; cell differentiation; ventral trunk neural crest cell migration; regulation of axon extension involved in axon guidance; semaphorin-plexin signaling pathway involved in neuron projection guidance; negative chemotaxis; neural crest cell migration involved in sympathetic nervous system development; sympathetic nervous system development; facioacoustic ganglion development; dendrite morphogenesis; trigeminal ganglion development; neuron migration; semaphorin-plexin signaling pathway involved in axon guidance; regulation of heart rate; nervous system development; axon guidance; multicellular organism development; sympathetic neuron projection guidance; neural crest cell migration involved in autonomic nervous system development; branchiomotor neuron axon guidance; gonadotrophin-releasing hormone neuronal migration to the hypothalamus; axonogenesis involved in innervation; dichotomous subdivision of terminal units involved in salivary gland branching; facial nerve structural organization; olfactory bulb development; motor neuron axon guidance; axonal fasciculation; negative regulation of epithelial cell migration; nerve development; trigeminal nerve structural organization; axon extension involved in axon guidance; semaphorin-plexin signaling pathway; sympathetic neuron projection extension; positive regulation of male gonad development; sensory system development; apoptotic process; negative regulation of neuron projection development; negative regulation of axon extension involved in axon guidance; positive regulation of neuron migration; neural crest cell migration; positive regulation of cell migration; positive regulation of JNK cascade; basal dendrite arborization;
	Sources:Amigo / QuickGO
Orthologs
	10371
	20346
	ENSG00000075213
	ENSMUSG00000028883
	Q14563
	O08665
	NM_006080
	NM_001243072; NM_001243073; NM_009152
	NP_006071
	NP_001230001; NP_001230002; NP_033178
	Wikidata
View/Edit Human	View/Edit Mouse

Semaphorin-3A is a protein that in humans is encoded by the SEMA3A gene.