SCN1A

SCN1A
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	7DTD
Identifiers
Aliases	SCN1A, EIEE6, FEB3, FEB3A, FHM3, GEFSP2, HBSCI, NAC1, Nav1.1, SCN1, SMEI, sodium voltage-gated channel alpha subunit 1, DRVT, DEE6, DEE6A, DEE6B
External IDs	OMIM: 182389; MGI: 98246; HomoloGene: 21375; GeneCards: SCN1A; OMA:SCN1A - orthologs
Gene location (Human)
Chr.	Chromosome 2 (human)
End	166,149,214 bp
Gene location (Mouse)
Chr.	Chromosome 2 (mouse)
End	66,271,184 bp
RNA expression pattern
	Top expressed in
	Brodmann area 23; ; lateral nuclear group of thalamus; ; primary visual cortex; ; pons; ; right uterine tube; ; endothelial cell; ; cerebellar vermis; ; superior vestibular nucleus; ; parietal lobe; ; postcentral gyrus;
	Top expressed in
	facial motor nucleus; ; lateral geniculate nucleus; ; medial vestibular nucleus; ; pontine nuclei; ; medial geniculate nucleus; ; anterior horn of spinal cord; ; deep cerebellar nuclei; ; inferior colliculi; ; superior colliculus; ; medial dorsal nucleus;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	sodium channel activity; voltage-gated ion channel activity; ion channel activity; voltage-gated sodium channel activity;
Cellular component	voltage-gated sodium channel complex; integral component of membrane; membrane; nucleoplasm; plasma membrane; nuclear body; intercalated disc; Z discdkac; T-tubule; axon; node of Ranvier; sodium channel complex; soma; axon initial segment;
Biological process	membrane depolarization during action potential; sodium ion transmembrane transport; regulation of ion transmembrane transport; ion transport; transmembrane transport; ion transmembrane transport; sodium ion transport; cardiac muscle cell action potential involved in contraction; action potential; adult walking behavior; neuronal action potential propagation; neuronal action potential; regulation of membrane potential; neuromuscular process controlling posture; detection of mechanical stimulus involved in sensory perception of pain;
	Sources:Amigo / QuickGO
Orthologs
	6323
	20265
	ENSG00000144285
	ENSMUSG00000064329
	P35498
	A2APX8
NM_001165963; NM_001165964; NM_001202435; NM_006920; NM_001353948;
	NM_001353949; NM_001353950; NM_001353951; NM_001353952; NM_001353954; NM_001353955; NM_001353957; NM_001353958; NM_001353960; NM_001353961
	NM_018733; NM_001313997
NP_001159435; NP_001159436; NP_001189364; NP_008851; NP_001340877;
	NP_001340878; NP_001340879; NP_001340880; NP_001340881; NP_001340883; NP_001340884; NP_001340886; NP_001340887; NP_001340889; NP_001340890
	NP_001300926; NP_061203
	Wikidata
View/Edit Human	View/Edit Mouse

Sodium channel protein type 1 subunit alpha (SCN1A), is a protein which in humans is encoded by the SCN1A gene.