S100A9

S100A9
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1IRJ, 1XK4, 4GGF, 4XJK
Identifiers
Aliases	S100A9, 60B8AG, CAGB, CFAG, CGLB, L1AG, LIAG, MAC387, MIF, MRP14, NIF, P14, S100 calcium binding protein A9, S100-A9
External IDs	OMIM: 123886; MGI: 1338947; HomoloGene: 2227; GeneCards: S100A9; OMA:S100A9 - orthologs
Gene location (Human)
Chr.	Chromosome 1 (human)
End	153,361,023 bp
Gene location (Mouse)
Chr.	Chromosome 3 (mouse)
End	90,603,028 bp
RNA expression pattern
	Top expressed in
	monocyte; ; granulocyte; ; periodontal fiber; ; bone marrow; ; oral cavity; ; mucosa of pharynx; ; gums; ; gingival epithelium; ; bone marrow cell; ; trabecular bone;
	Top expressed in
	granulocyte; ; tibiofemoral joint; ; ankle joint; ; femur; ; body of femur; ; fetal liver hematopoietic progenitor cell; ; spleen; ; blood; ; vestibular membrane of cochlear duct; ; human fetus;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	calcium ion binding; microtubule binding; zinc ion binding; signal transducer activity; metal ion binding; Toll-like receptor 4 binding; antioxidant activity; protein binding; RAGE receptor binding; arachidonic acid binding;
Cellular component	membrane; plasma membrane; extracellular exosome; cytoskeleton; nucleus; extracellular matrix; extracellular space; nucleoplasm; cytosol; cell junction; secretory granule lumen; cytoplasm; extracellular region; collagen-containing extracellular matrix;
Biological process	peptidyl-cysteine S-trans-nitrosylation; positive regulation of inflammatory response; chemokine production; immune system process; cellular oxidant detoxification; cell-cell signaling; cytokine production; leukocyte migration involved in inflammatory response; neutrophil chemotaxis; defense response to fungus; chemotaxis; sequestering of zinc ion; neutrophil aggregation; positive regulation of cell growth; defense response to bacterium; positive regulation of NF-kappaB transcription factor activity; regulation of inflammatory response; innate immune response; inflammatory response; activation of cysteine-type endopeptidase activity involved in apoptotic process; positive regulation of intrinsic apoptotic signaling pathway; regulation of cytoskeleton organization; apoptotic process; autophagy; toll-like receptor signaling pathway; antimicrobial humoral response; neutrophil degranulation; positive regulation of neuron projection development;
	Sources:Amigo / QuickGO
Orthologs
	6280
	20202
	ENSG00000163220
	ENSMUSG00000056071
	P06702
	P31725
	NM_002965
	NM_001281852; NM_009114
	NP_002956
	NP_001268781; NP_033140
	Wikidata
View/Edit Human	View/Edit Mouse

S100 calcium-binding protein A9 (S100A9) also known as migration inhibitory factor-related protein 14 (MRP14) or calgranulin B is a protein that in humans is encoded by the S100A9 gene.

The proteins S100A8 and S100A9 form a heterodimer called calprotectin.