40S ribosomal protein S3

RPS3
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1WH9, 4UG0, 4V6X, 5A2Q, 5AJ0, 3J7P, 4UJE, 4D5L, 3J7R, 4UJD, 4V5Z, 5FLX, 4D61, 4UJC
Identifiers
Aliases	RPS3, S3, ribosomal protein S3
External IDs	OMIM: 600454; MGI: 1350917; HomoloGene: 779; GeneCards: RPS3; OMA:RPS3 - orthologs
Gene location (Human)
Chr.	Chromosome 11 (human)
End	75,422,280 bp
Gene location (Mouse)
Chr.	Chromosome 7 (mouse)
End	99,132,945 bp
RNA expression pattern
	Top expressed in
	left ovary; ; right ovary; ; right uterine tube; ; ventricular zone; ; ganglionic eminence; ; canal of the cervix; ; epithelium of colon; ; stromal cell of endometrium; ; granulocyte; ; body of uterus;
	Top expressed in
	otic vesicle; ; epidermis; ; tracheobronchial tree; ; autopod region; ; mesenteric lymph nodes; ; hand; ; ovary; ; trachea; ; ventricular zone; ; lactiferous gland;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	tubulin binding; DNA N-glycosylase activity; small ribosomal subunit rRNA binding; iron-sulfur cluster binding; transcription factor binding; oxidized purine DNA binding; Hsp70 protein binding; lyase activity; enzyme binding; mRNA binding; structural constituent of ribosome; damaged DNA binding; ubiquitin-like protein conjugating enzyme binding; protein binding; DNA-(apurinic or apyrimidinic site) endonuclease activity; oxidized pyrimidine DNA binding; endodeoxyribonuclease activity; protein kinase binding; supercoiled DNA binding; DNA binding; Hsp90 protein binding; microtubule binding; protein kinase A binding; RNA binding; kinase binding; RNA polymerase II transcription regulatory region sequence-specific DNA binding; protein-containing complex binding; class I DNA-(apurinic or apyrimidinic site) endonuclease activity; class III/IV DNA-(apurinic or apyrimidinic site) endonuclease activity; oxidized purine nucleobase lesion DNA N-glycosylase activity;
Cellular component	cytoplasm; cytosol; polysome; membrane; focal adhesion; ruffle membrane; mitochondrion; cytoskeleton; nucleus; ribosome; nucleolus; extracellular exosome; plasma membrane; spindle; mitochondrial matrix; small ribosomal subunit; mitotic spindle; mitochondrial inner membrane; cytosolic small ribosomal subunit; nucleoplasm; extracellular matrix; endoplasmic reticulum; NF-kappaB complex; postsynaptic density; ribonucleoprotein complex; synapse;
Biological process	chromosome segregation; positive regulation of endodeoxyribonuclease activity; cellular response to DNA damage stimulus; positive regulation of microtubule polymerization; cell cycle; apoptotic process; negative regulation of translation; regulation of transcription, DNA-templated; viral transcription; response to TNF agonist; positive regulation of apoptotic signaling pathway; response to oxidative stress; transcription, DNA-templated; SRP-dependent cotranslational protein targeting to membrane; positive regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis; positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage; positive regulation of DNA N-glycosylase activity; positive regulation of JUN kinase activity; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; negative regulation of DNA repair; positive regulation of DNA repair; positive regulation of NIK/NF-kappaB signaling; cell division; spindle assembly; negative regulation of protein ubiquitination; positive regulation of gene expression; translational initiation; regulation of translation; cellular response to hydrogen peroxide; protein biosynthesis; positive regulation of base-excision repair; DNA repair; regulation of apoptotic process; rRNA processing; cytoplasmic translation; positive regulation of protein-containing complex assembly; positive regulation of interleukin-2 production; positive regulation of activated T cell proliferation; positive regulation of T cell receptor signaling pathway; positive regulation of NF-kappaB transcription factor activity; cellular response to tumor necrosis factor;
	Sources:Amigo / QuickGO
Orthologs
	6188
	27050
	ENSG00000149273
	ENSMUSG00000030744
	P23396
	P62908
	NM_001260507; NM_001005; NM_001256802; NM_001260506
	NM_012052
	NP_000996; NP_001243731; NP_001247435; NP_001247436
	NP_036182
	Wikidata
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40S ribosomal protein S3 is a protein that in humans is encoded by the RPS3 gene.