RU-27251

RU-27251
Clinical data
Other names	RU27251; 3,5-Secoergoline
Drug class	Serotonin receptor modulator; Dopamine receptor modulator; Partial ergoline
ATC code	None;
Identifiers
	IUPAC name 4-piperidin-3-yl-1H-indole;
CAS Number	81887-47-0 ; 81887-48-1; 16176-75-3;
PubChem CID	3067718;
ChemSpider	2327800;
CompTox Dashboard (EPA)	DTXSID501002284 ;
Chemical and physical data
Formula	C13H16N2
Molar mass	200.285 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES C1CC(CNC1)C2=C3C=CNC3=CC=C2;
	InChI InChI=1S/C13H16N2/c1-4-11(10-3-2-7-14-9-10)12-6-8-15-13(12)5-1/h1,4-6,8,10,14-15H,2-3,7,9H2; Key:JWMGZQMVMZBMFM-UHFFFAOYSA-N;

RU-27251, also known as 3,5-secoergoline or as 4-piperidin-3-yl-1H-indole, is a serotonin receptor modulator and dopamine receptor agonist of the partial ergoline family. Its affinity (K_D) for the dopamine D₂^high receptor was 72 nM and for the dopamine D₂^low receptor was 11,600 nM. RU-27251 was first described in the scientific literature by 1983.