Purine nucleoside phosphorylase
| purine-nucleoside phosphorylase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
purine-nucleoside phosphorylase. PDB 1rct. | |||||||||
| Identifiers | |||||||||
| EC no. | 2.4.2.1 | ||||||||
| CAS no. | 9030-21-1 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
Purine nucleoside phosphorylase, PNP, PNPase or inosine phosphorylase (EC 2.4.2.1) is an enzyme that in humans is encoded by the PNP gene. It catalyzes the chemical reaction
- Purine Nucleoside + Inorganic Phosphate (Pi) Purine Base + α-D-Ribose 1-Phosphate
The enzyme catalyzes reversible interconversion of purine nucleoside and phosphate into purine base and α-D-ribose 1-phosphate.