Proprotein convertase subtilisin/kexin type 1 inhibitor

PCSK1N
Identifiers
Aliases	PCSK1N, PROSAAS, SAAS, SCG8, SgVIII, BigLEN, PEN, proprotein convertase subtilisin/kexin type 1 inhibitor
External IDs	OMIM: 300399; MGI: 1353431; HomoloGene: 8315; GeneCards: PCSK1N; OMA:PCSK1N - orthologs
Gene location (Human)
Chr.	X chromosome (human)
End	48,835,610 bp
Gene location (Mouse)
Chr.	X chromosome (mouse)
End	7,790,649 bp
RNA expression pattern
	Top expressed in
	anterior pituitary; ; beta cell; ; nucleus accumbens; ; anterior cingulate cortex; ; amygdala; ; right frontal lobe; ; caudate nucleus; ; hypothalamus; ; putamen; ; dorsolateral prefrontal cortex;
	Top expressed in
	entorhinal cortex; ; perirhinal cortex; ; median eminence; ; central gray substance of midbrain; ; arcuate nucleus; ; ventromedial nucleus; ; dorsomedial hypothalamic nucleus; ; superior colliculus; ; dorsal tegmental nucleus; ; mammillary body;
	More reference expression data
	n/a
Gene ontology
Molecular function	endopeptidase inhibitor activity; signaling receptor binding; serine-type endopeptidase inhibitor activity;
Cellular component	extracellular region; trans-Golgi network; Golgi apparatus; secretory granule; extracellular space;
Biological process	response to dietary excess; response to cold; neuropeptide signaling pathway; peptide hormone processing; negative regulation of endopeptidase activity;
	Sources:Amigo / QuickGO
Orthologs
	27344
	30052
	ENSG00000102109
	ENSMUSG00000039278
	Q9UHG2
	Q9QXV0
	NM_013271
	NM_013892
	NP_037403
	NP_038920
	Wikidata
View/Edit Human	View/Edit Mouse

Proprotein convertase subtilisin/kexin type 1 inhibitor is a protein by the name of proSAAS that in humans is encoded by the PCSK1N gene.