Primase
| Toprim domain | |||||||
|---|---|---|---|---|---|---|---|
| Identifiers | |||||||
| Symbol | Toprim | ||||||
| Pfam | PF01751 | ||||||
| Pfam clan | Toprim-like | ||||||
| InterPro | IPR006171 | ||||||
| SCOP2 | 2fcj / SCOPe / SUPFAM | ||||||
| |||||||
| Toprim catalytic core | |||||||
|---|---|---|---|---|---|---|---|
| Identifiers | |||||||
| Symbol | Toprim_N | ||||||
| Pfam | PF08275 | ||||||
| InterPro | IPR013264 | ||||||
| SCOP2 | 1dd9 / SCOPe / SUPFAM | ||||||
| |||||||
| AEP DNA primase, small subunit | |||||||
|---|---|---|---|---|---|---|---|
| Identifiers | |||||||
| Symbol | DNA_primase_S | ||||||
| Pfam | PF01896 | ||||||
| Pfam clan | AEP | ||||||
| InterPro | IPR002755 | ||||||
| SCOP2 | 1g71 / SCOPe / SUPFAM | ||||||
| |||||||
| AEP DNA primase, large subunit | |||||||
|---|---|---|---|---|---|---|---|
| Identifiers | |||||||
| Symbol | DNA_primase_lrg | ||||||
| Pfam | PF04104 | ||||||
| Pfam clan | CL0242 | ||||||
| InterPro | IPR007238 | ||||||
| SCOP2 | 1zt2 / SCOPe / SUPFAM | ||||||
| |||||||
DNA primase is an enzyme involved in the replication of DNA and is a type of RNA polymerase. Primase catalyzes the synthesis of a short RNA (or DNA in some living organisms) segment called a primer complementary to a ssDNA (single-stranded DNA) template. After this elongation, the RNA piece is removed by a 5' to 3' exonuclease and refilled with DNA.