La Crosse, Wisconsin

La Crosse, Wisconsin
Interactive map of La Crosse, Wisconsin
La Crosse
La Crosse
Coordinates: 43°48′48″N 91°13′59″W / 43.81333°N 91.23306°W / 43.81333; -91.23306
CountryUnited States
StateWisconsin
CountyLa Crosse
Established1842
Government
 • TypeMayor-council government
 • MayorShaundel Washington-Spivey (D)
Area
 • City
23.79 sq mi (61.61 km2)
 • Land21.70 sq mi (56.21 km2)
 • Water2.08 sq mi (5.40 km2)
Elevation
669 ft (204 m)
Population
 (2020)
 • City
52,680
 • Estimate 
(2024)
51,049
 • RankUS: 763rd
WI: 12th
 • Density2,360.4/sq mi (911.34/km2)
 • Urban
98,872 (US: 314th)
 • Metro
139,211 (US: 299th)
Time zoneUTC−6 (Central)
 • Summer (DST)UTC−5 (Central)
Zip Code
54601, 54602, 54603
Area code608
FIPS code55-40775
GNIS feature ID1567672
WaterwaysMississippi River, Black River, La Crosse River
Public TransitLa Crosse MTU
SMRT
Amtrak
Websitewww.cityoflacrosse.org

La Crosse (/ləˈkrɒs/ lə-KROSS) is a city in La Crosse County, Wisconsin, United States, and its county seat. Positioned alongside the Mississippi River, La Crosse is the most populous city on Wisconsin's western border. The population was 52,680 at the 2020 census. The La Crosse–Onalaska metropolitan area has an estimated 140,000 residents.

La Crosse's economy serves as a regional educational, medical, manufacturing, and transportation hub for Western Wisconsin producing a gross domestic product (GDP) of $10.1 billion for the La Crosse–Onalaska metropolitan area as of 2023. Home to the University of Wisconsin–La Crosse, Viterbo University, and Western Technical College, the city has nearly 20,000 students. The La Crosse area is home to the headquarters or regional offices of Kwik Trip, Organic Valley, Mayo Clinic, Gundersen Health System, Gensler, La Crosse Technology, City Brewing Company, and Trane.