Post-transcriptional regulation

Not to be confused with Post-translational regulation.

Post-transcriptional regulation is the control of gene expression at the RNA level.The information in DNA is converted in to mRNA and this newly synthesized mRNA undergo a series of modifications before the information in mRNA is converted in to functional protein, this phenomenon is known as Post-transcriptional regulation. It occurs once the RNA polymerase has been attached to the gene's promoter and is synthesizing the RNA sequence by the process known as transcription and, therefore it is named as post transcriptional regulation. Post-transcriptional regulation significantly affects transcript level, function, structure and expression of final proteins.

Importance

These controls are critical for the regulation of many genes across human tissues. It also plays a big role in cell physiology, being implicated in pathologies such as cancer and neurodegenerative diseases.

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