Point spread function
The point spread function (PSF) describes the response of a focused optical imaging system to an idealized point source of light. In casual terms, for a given camera, it is the blurry blob image captured from pointing that camera at a single speck of light.
More technically, a PSF is a form of impulse response function (IRF) for a focused optical imaging system, in spatial terms (as opposed to temporal terms). In functional terms, it is the spatial domain version (i.e., the inverse Fourier transform) of the optical transfer function (OTF) of an imaging system. It is a useful concept in Fourier optics, astronomical imaging, medical imaging, electron microscopy and other imaging techniques such as 3D microscopy (like in confocal laser scanning microscopy) and fluorescence microscopy.
The degree of spreading (blurring) in the image of a point object for an imaging system is a measure of the quality of the imaging system. In non-coherent imaging systems, such as fluorescent microscopes, telescopes or optical microscopes, the image formation process is linear in the image intensity and described by a linear system theory. This means that when two objects A and B are imaged simultaneously by a non-coherent imaging system, the resulting image is equal to the sum of the independently imaged objects. In other words: the imaging of A is unaffected by the imaging of B and vice versa, owing to the non-interacting property of photons. In space-invariant systems, i.e. those in which the PSF is the same everywhere in the imaging space, the image of a complex object is then the convolution of that object and the PSF. The PSF can be derived from diffraction integrals.