Perlatolic acid

Perlatolic acid
Names
IUPAC name
2-hydroxy-4-(2-hydroxy-4-methoxy-6-pentylbenzoyl)oxy-6-pentylbenzoic acid
Other names
Perlatolinic acid
Identifiers
3D model (JSmol)
ChEBI
ChEMBL
ChemSpider
  • InChI=1S/C25H32O7/c1-4-6-8-10-16-13-19(15-20(26)22(16)24(28)29)32-25(30)23-17(11-9-7-5-2)12-18(31-3)14-21(23)27/h12-15,26-27H,4-11H2,1-3H3,(H,28,29)
    Key: UTAQXQVSEKIWBB-UHFFFAOYSA-N
  • CCCCC1=C(C(=CC(=C1)OC)O)C(=O)OC2=CC(=C(C(=C2)O)C(=O)O)CCCCC
Properties
C25H32O7
Molar mass 444.5 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

Perlatolic acid is a lichen secondary metabolite belonging to the depside class. It has been reported from several lichens, including species in the family Parmeliaceae and reindeer lichens such as Cladonia stellaris. The compound has a low first dissociation constant, which has been linked to the ability of some perlatolic acid-containing lichens to persist on very acidic substrates and under acidic air pollution. In laboratory studies, perlatolic acid derivatives have shown phytotoxic/herbicidal effects, and perlatolic acid itself has shown in vitro antiviral activity against human coronaviruses.