Penicillin-binding proteins

Penicillin-binding protein, dimerisation domain
Penicillin-binding protein, dimerisation domain
Identifiers
Symbol	PBP_dimer
Pfam	PF03717
InterPro	IPR005311
PDB
Available protein structures:
PDB	PDB: 1k25 PDB: 1mwr PDB: 1mws PDB: 1mwt PDB: 1mwu PDB: 1pmd PDB: 1pyy PDB: 1qme PDB: 1qmf PDB: 1rp5 IPR005311 PF03717 (ECOD; PDBsum)
AlphaFold	IPR005311; PF03717;

Available protein structures:
PDB	IPR001460 PF00905 (ECOD; PDBsum)
AlphaFold	IPR001460; PF00905;

Penicillin-binding protein, transpeptidase
Penicillin-binding protein, transpeptidase
Identifiers
Symbol	PCN-bd_Tpept
Pfam	PF00905
InterPro	IPR001460
OPM superfamily	195
OPM protein	5hlb
Membranome	541
PDB
Available protein structures:
PDB	IPR001460 PF00905 (ECOD; PDBsum)
AlphaFold	IPR001460; PF00905;

Penicillin-binding proteins (PBPs) are a group of proteins that are characterized by their affinity for and binding of penicillin. They are a normal constituent of many bacteria; the name just reflects the way by which the protein was discovered. All β-lactam antibiotics (except for tabtoxinine-β-lactam, which inhibits glutamine synthetase) bind to PBPs, which are essential for bacterial cell wall synthesis. PBPs are members of a subgroup of transpeptidase enzymes called DD-transpeptidases.