Parvalbumin

Available protein structures:
PDB	IPR008080
AlphaFold	IPR008080;

Parvalbumin
Parvalbumin
Identifiers
Symbol	?
InterPro	IPR008080
PDB
Available protein structures:
PDB	IPR008080
AlphaFold	IPR008080;

PVALB
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1RJV, 1RK9,%%s1RK9, 1RJV
Identifiers
Aliases	PVALB, D22S749, parvalbumin
External IDs	OMIM: 168890; MGI: 97821; HomoloGene: 2137; GeneCards: PVALB; OMA:PVALB - orthologs
Gene location (Human)
Chr.	Chromosome 22 (human)
End	36,819,479 bp
Gene location (Mouse)
Chr.	Chromosome 15 (mouse)
End	78,090,600 bp
RNA expression pattern
	Top expressed in
	right hemisphere of cerebellum; ; primary visual cortex; ; superior frontal gyrus; ; dorsolateral prefrontal cortex; ; right frontal lobe; ; muscle of thigh; ; human kidney; ; substantia nigra; ; Brodmann area 9; ; C1 segment;
	Top expressed in
	triceps brachii muscle; ; temporal muscle; ; sternocleidomastoid muscle; ; digastric muscle; ; muscle of thigh; ; medial head of gastrocnemius muscle; ; vastus lateralis muscle; ; tibialis anterior muscle; ; ankle joint; ; ankle;
	More reference expression data
	n/a
Gene ontology
Molecular function	calcium ion binding; protein homodimerization activity; metal ion binding; protein heterodimerization activity;
Cellular component	cytoplasm; axon; soma; nucleus; protein-containing complex; stereocilium; cuticular plate;
Biological process	regulation of cytosolic calcium ion concentration; cochlea development;
	Sources:Amigo / QuickGO
Orthologs
	5816
	19293
	ENSG00000274665; ENSG00000100362
	ENSMUSG00000005716
	P20472
	P32848
	NM_002854; NM_001315532
	NM_013645; NM_001330686
	NP_001302461; NP_002845; NP_001302461.1; NP_002845.1
	NP_001317615; NP_038673
	Wikidata
View/Edit Human	View/Edit Mouse

Parvalbumin (PV) is a calcium-binding protein with low molecular weight (typically 9–11 kDa). In humans, it is encoded by the PVALB gene. It is a member of the albumin family; it is named for its size (parv-, from Latin parvus which means "small") and its ability to coagulate.

It has three EF hand motifs and is structurally related to calmodulin and troponin C. Parvalbumin is found in fast-contracting muscles, where its levels are highest, as well as in the brain and some endocrine tissues.