PTPRA

PTPRA
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1P15, 1YFO
Identifiers
Aliases	PTPRA, HEPTP, HLPR, HPTPA, HPTPalpha, LRP, PTPA, PTPRL2, R-PTP-alpha, RPTPA, protein tyrosine phosphatase, receptor type A, protein tyrosine phosphatase receptor type A
External IDs	OMIM: 176884; MGI: 97808; HomoloGene: 20621; GeneCards: PTPRA; OMA:PTPRA - orthologs
Gene location (Human)
Chr.	Chromosome 20 (human)
End	3,039,076 bp
Gene location (Mouse)
Chr.	Chromosome 2 (mouse)
End	130,398,044 bp
RNA expression pattern
	Top expressed in
	Achilles tendon; ; ventricular zone; ; ganglionic eminence; ; right frontal lobe; ; prefrontal cortex; ; nucleus accumbens; ; right hemisphere of cerebellum; ; amygdala; ; cingulate gyrus; ; anterior cingulate cortex;
	Top expressed in
	dentate gyrus of hippocampal formation granule cell; ; stroma of bone marrow; ; epithelium of lens; ; superior frontal gyrus; ; ventricular zone; ; subiculum; ; right kidney; ; primary visual cortex; ; cerebellar cortex; ; nucleus accumbens;
	More reference expression data
	n/a
Gene ontology
Molecular function	protein binding; phosphatase activity; protein tyrosine phosphatase activity; phosphoprotein phosphatase activity; transmembrane receptor protein tyrosine phosphatase activity; hydrolase activity;
Cellular component	receptor complex; integral component of plasma membrane; integral component of membrane; membrane; extracellular exosome; plasma membrane; intracellular anatomical structure; Schaffer collateral - CA1 synapse; integral component of synaptic membrane;
Biological process	dephosphorylation; axon guidance; protein phosphorylation; protein dephosphorylation; MAPK cascade; peptidyl-tyrosine dephosphorylation; insulin receptor signaling pathway; regulation of molecular function; modulation of chemical synaptic transmission;
	Sources:Amigo / QuickGO
Orthologs
	5786
	19262
	ENSG00000132670
	ENSMUSG00000027303
	P18433; Q5JWG0
	P18052
	NM_080841; NM_002836; NM_080840
	NM_001163688; NM_008980; NM_001355161
	NP_002827; NP_543030; NP_543031
	NP_001157160; NP_033006; NP_001342090
	Wikidata
View/Edit Human	View/Edit Mouse

Receptor-type tyrosine-protein phosphatase alpha is an enzyme that in humans is encoded by the PTPRA gene.