PNU-22394

PNU-22394
Clinical data
Other names	PNU22394; PNU-22394A; PNU22394A; U-22394A; U22394A
Routes of; administration	Oral
Drug class	Serotonin 5-HT2C receptor agonist; Non-hallucinogenic serotonin 5-HT2A receptor agonist; Serotonin 5-HT2B receptor weak partial agonist or antagonist
Identifiers
	IUPAC name 6-methyl-1,2,3,4,5,6-hexahydro-azepino[4,5-b]indole;
CAS Number	15923-78-1 ;
PubChem CID	27559;
ChemSpider	25649 ;
UNII	J7HPJ854EA;
ChEMBL	ChEMBL6557 ;
CompTox Dashboard (EPA)	DTXSID001028489 ;
Chemical and physical data
Formula	C13H16N2
Molar mass	200.285 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES C3CNCCc2c3c1ccccc1n2C;
	InChI InChI=1S/C13H16N2/c1-15-12-5-3-2-4-10(12)11-6-8-14-9-7-13(11)15/h2-5,14H,6-9H2,1H3 ; Key:ZBXDOQWPGBISAR-UHFFFAOYSA-N ;
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PNU-22394, or PNU-22394A, also known as U-22394A, as well as 6-methyl-1,2,3,4,5,6-hexahydroazepino[4,5-b]indole, is a serotonin 5-HT₂ receptor agonist of the ibogalog family which was studied as an appetite suppressant and antipsychotic but was never marketed. As an ibogalog, PNU-22394 is a cyclized tryptamine and a simplified ibogaine analogue.