Ofornine

Ofornine
Clinical data
Other namesWin 48049
Identifiers
  • 1-Piperidinyl(2-(4-pyridinylamino)phenyl)methanone
CAS Number
PubChem CID
ChemSpider
UNII
KEGG
ChEMBL
CompTox Dashboard (EPA)
ECHA InfoCard100.081.195
Chemical and physical data
FormulaC17H19N3O
Molar mass281.359 g·mol−1
3D model (JSmol)
  • C1CCN(CC1)C(=O)C2=CC=CC=C2NC3=CC=NC=C3
  • InChI=1S/C17H19N3O/c21-17(20-12-4-1-5-13-20)15-6-2-3-7-16(15)19-14-8-10-18-11-9-14/h2-3,6-11H,1,4-5,12-13H2,(H,18,19)
  • Key:YMODINPJYNHPTM-UHFFFAOYSA-N

Ofornine is a synthetic compound investigated primarily for its antihypertensive properties. It functions as a vasodilator and exhibits presynaptic adrenolytic activity, with evidence suggesting involvement of dopaminergic mechanisms in its pharmacological effects.

A number of structural analogs have been prepared with similar activity.