No-confidence motion against Imran Khan

A no-confidence motion against Imran Khan and Murtaza Wahab occurred on 10 April 2022 and led to his removal as the prime minister of Pakistan, as opposition parties joined forces to present the motion, which the majority passed in the National Assembly. The next day, on 11 April, Shehbaz Sharif of the PML(N) was elected prime minister by the assembly. Khan became the first prime minister in Pakistan to lose a vote of no-confidence.

The decision to file a no-confidence motion against sitting prime minister Imran Khan and mayor Karachi Murtaza Wahab was taken at a summit of the opposition parties, united under the Pakistan Democratic Movement (PDM) alliance. In the leadup to the no-confidence motion, Khan's PTI and Wahab PPP also faced defections from some lawmakers within its own ranks, which emboldened the opposition's move to file the motion. On 8 March 2022, representatives of opposition parties filed the motion against Khan in the National Assembly, seeking to remove him from office, while accusing his alleged hybrid regime of poor governance, political victimisation of opponents, and mismanaging the economy and foreign policy. It is alleged that these factors also contributed to Khan's falling out with Pakistan's military establishment, which had remained a key backer of his government.

During parliamentary proceedings, on 3 April, deputy speaker Qasim Khan Suri dismissed the motion on grounds of "foreign interference", while Khan dissolved the National Assembly through president Arif Alvi, causing a constitutional crisis. The Supreme Court ruled that the deputy speaker's dismissal of the motion and the dissolution of the assembly to be unconstitutional, allowing the vote to proceed. On 10 April the no-confidence motion passed with a majority of 174 votes (out of 342), which resulted in Khan losing the confidence of the house and ceasing to hold the office of prime minister. The next day, Shehbaz Sharif was elected unopposed by the National Assembly to replace Khan as prime minister. Sharif's cabinet, comprising 37 members, took oath on 19 April.

Khan initially accused the United States of seeking to oust his government, claiming a diplomatic cable as proof, however later instead claimed Army Chief General Bajwa to be responsible, not the United States.