National Space Biomedical Research Institute

The National Space Biomedical Research Institute (NSBRI) was a NASA-funded consortium of institutions studying the health risks related to long-duration spaceflight and developing solutions to reduce those risks. The NSBRI was founded in 1997 through a NASA Cooperative Agreement. The founding director was Laurence R. Young of MIT. The original headquarters office was in the Neurosensory Center Building in the Texas Medical Center in Houston. NSBRI later moved to its 16,400-square-foot headquarters facility located in the BioScience Research Collaborative in Houston, Texas. The Institute shared the facility with Baylor College of Medicine's Center for Space Medicine. The official opening was held March 19, 2012.

In March 2012 NASA announced a five-year extension of its cooperative agreement with NSBRI. At the end of this period NASA wound down its relationship with NSBRI, which closed in 2017. The consortium was succeeded by the Translational Research Institute for Space Health (TRISH), led by the Baylor College of Medicine.