Nancy Bonini

Nancy Bonini
Born
Nancy M. Bonini

1959 (age 66–67)
EducationPrinceton University (AB)
University of Wisconsin-Madison (PhD)
Known forDeveloped the first Drosophila model of human neurodenerative disease
SpouseAnthony Cashmore
Awards
Scientific career
Fields
InstitutionsCalifornia Institute of Technology
University of Pennsylvania
Doctoral advisorDavid L. Nelson

Nancy M. Bonini (born 1959) is an American neuroscientist and geneticist, best known for pioneering the use of Drosophila as a model organism to study neurodegeneration of the human brain. Using the Drosophila model approach, Bonini's laboratory has identified genes and pathways that are important in the development and progression of neurodegenerative diseases such as Amyotrophic lateral sclerosis (ALS, also called Lou Gehrig's Disease), Alzheimer's disease, and Parkinson's disease, as well as aging, neural injury and regeneration, and response to environmental toxins.

A professor of biology at the University of Pennsylvania since 1994, Bonini has held appointments as the inaugural Lucille B. Williams Term Professor of Biology (2006–2012), an Investigator of the Howard Hughes Medical Institute (2000–2013), and the Florence RC Murray Professor of Biology (since 2012). She was editor of the Annual Review of Genetics from 2018-2021.