Neuropeptide FF receptor 2

NPFFR2
Identifiers
Aliases	NPFFR2, GPR74, HLWAR77, NPFF2, NPGPR, neuropeptide FF receptor 2
External IDs	OMIM: 607449; MGI: 1860130; HomoloGene: 56982; GeneCards: NPFFR2; OMA:NPFFR2 - orthologs
Gene location (Human)
Chr.	Chromosome 4 (human)
End	72,148,305 bp
Gene location (Mouse)
Chr.	Chromosome 5 (mouse)
End	89,731,599 bp
RNA expression pattern
	Top expressed in
	gonad; ; testicle; ; placenta; ; islet of Langerhans; ; prefrontal cortex; ; parietal pleura; ; gastric mucosa; ; seminal vesicula; ; Brodmann area 9; ; appendix;
	Top expressed in
	primary oocyte; ; zygote; ; secondary oocyte; ; embryo; ; spinal ganglia; ; blastocyst; ; olfactory bulb; ; mandibular prominence; ; testicle; ; trigeminal ganglion;
	More reference expression data
	n/a
Gene ontology
Molecular function	opioid receptor binding; peptide binding; G protein-coupled receptor activity; signal transducer activity; neuropeptide receptor activity;
Cellular component	integral component of membrane; plasma membrane; integral component of plasma membrane; membrane; actin cytoskeleton;
Biological process	G protein-coupled receptor signaling pathway; detection of abiotic stimulus; cellular response to hormone stimulus; regulation of MAPK cascade; regulation of adenylate cyclase activity; regulation of cAMP-dependent protein kinase activity; signal transduction; response to peptide; neuropeptide signaling pathway;
	Sources:Amigo / QuickGO
Orthologs
	10886
	104443
	ENSG00000056291
	ENSMUSG00000035528
	Q9Y5X5
	Q924H0
	NM_001144756; NM_004885; NM_053036
	NM_133192
	NP_001138228; NP_004876; NP_444264
	NP_573455
	Wikidata
View/Edit Human	View/Edit Mouse

Neuropeptide FF receptor 2, also known as NPFF2 and formerly as GPR74, is a human protein encoded by the NPFFR2 gene.