NFKB2

NFKB2
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1A3Q, 2D96, 3DO7, 4OT9
Identifiers
Aliases	NFKB2, CVID10, H2TF1, LYT-10, LYT10, NF-kB2, p105, p52, p100, p49/p100, nuclear factor kappa B subunit 2
External IDs	OMIM: 164012; MGI: 1099800; HomoloGene: 1873; GeneCards: NFKB2; OMA:NFKB2 - orthologs
Gene location (Human)
Chr.	Chromosome 10 (human)
End	102,402,524 bp
Gene location (Mouse)
Chr.	Chromosome 19 (mouse)
End	46,300,824 bp
RNA expression pattern
	Top expressed in
	granulocyte; ; muscle layer of sigmoid colon; ; spleen; ; epithelium of colon; ; monocyte; ; left uterine tube; ; lymph node; ; upper lobe of left lung; ; gallbladder; ; sural nerve;
	Top expressed in
	mesenteric lymph nodes; ; granulocyte; ; spleen; ; aortic valve; ; cumulus cell; ; ascending aorta; ; motor neuron; ; thymus; ; lip; ; renal vein;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	DNA binding; DNA-binding transcription factor activity; transcription coactivator activity; DNA-binding transcription activator activity, RNA polymerase II-specific; chromatin binding; RNA polymerase II cis-regulatory region sequence-specific DNA binding; protein binding; DNA-binding transcription factor activity, RNA polymerase II-specific;
Cellular component	cytoplasm; Bcl3/NF-kappaB2 complex; nucleus; nucleoplasm; cytosol;
Biological process	response to cytokine; regulation of transcription, DNA-templated; rhythmic process; germinal center formation; ageing; extracellular matrix organization; negative regulation of transcription by RNA polymerase II; spleen development; transcription, DNA-templated; follicular dendritic cell differentiation; response to lipopolysaccharide; NIK/NF-kappaB signaling; positive regulation of NF-kappaB transcription factor activity; inflammatory response; I-kappaB kinase/NF-kappaB signaling; positive regulation of type I interferon production; positive regulation of transcription by RNA polymerase II; signal transduction; transcription by RNA polymerase II; innate immune response;
	Sources:Amigo / QuickGO
Orthologs
	4791
	18034
	ENSG00000077150
	ENSMUSG00000025225
	Q00653
	Q9WTK5
NM_001077494; NM_001261403; NM_001288724; NM_002502; NM_001322934;
	NM_001322935
	NM_001177369; NM_001177370; NM_019408
NP_001070962; NP_001248332; NP_001275653; NP_001309863; NP_001309864;
	NP_002493
	NP_001170840; NP_001170841; NP_062281
	Wikidata
View/Edit Human	View/Edit Mouse

Nuclear factor NF-kappa-B p100 subunit is a protein that in humans is encoded by the NFKB2 gene.