NEFA (drug)

NEFA
Identifiers
  • (4aR,9aS)-N-Ethyl-4,4a,9,9a-tetrahydro-1H-fluoren-4a-amine
CAS Number
PubChem CID
UNII
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC15H19N
Molar mass213.324 g·mol−1
3D model (JSmol)
  • CCN[C@]12CC=CC[C@H]1CC3=CC=CC=C23
  • InChI=1S/C15H19N/c1-2-16-15-10-6-5-8-13(15)11-12-7-3-4-9-14(12)15/h3-7,9,13,16H,2,8,10-11H2,1H3/t13-,15+/m0/s1
  • Key:DRCWOKJLSQUJPZ-DZGCQCFKSA-N
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NEFA is a moderate affinity NMDA antagonist (IC50 = 0.51 μM). It is a structural analog of phencyclidine. It was first synthesized by a team at Parke-Davis in the late 1950s.

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