N⁴-Acetylcytidine

N⁴-Acetylcytidine
Names
	IUPAC name N-[1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-2-oxopyrimidin-4-yl]acetamide
	Other names ac4C; N-acetylcytidine;
Identifiers
CAS Number	3768-18-1;
3D model (JSmol)	Interactive image;
ChEBI	CHEBI:70989;
ChemSpider	96702;
ECHA InfoCard	100.021.087
EC Number	223-195-6;
KEGG	C22293;
PubChem CID	107461;
CompTox Dashboard (EPA)	DTXSID40958718 ;
	InChI InChI=1S/C11H15N3O6/c1-5(16)12-7-2-3-14(11(19)13-7)10-9(18)8(17)6(4-15)20-10/h2-3,6,8-10,15,17-18H,4H2,1H3,(H,12,13,16,19)/t6-,8-,9-,10-/m1/s1 Key: NIDVTARKFBZMOT-PEBGCTIMSA-N;
	SMILES CC(=O)NC1=NC(=O)N(C=C1)[C@H]2[C@@H]([C@@H]([C@H](O2)CO)O)O;
Properties
Chemical formula	C11H15N3O6
Molar mass	285.256 g·mol−1
Appearance	white amorphous solid, sometimes yellow/brown
Density	1.72 g/cm3
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). Infobox references

N⁴-Acetylcytidine (ac4C, ac⁴C) is a post-transcriptional modification found in tRNAs, rRNAs, and mRNAs. In this modification, the amino group at the N⁴ position of the RNA base cytosine is acetylated, resulting in the formation of an amide. In vivo, this modification is considered highly conserved because it is seen in all three domains of life: archaea, bacteria, and eukarya.