Missouri's 1st congressional district

Missouri's 1st congressional district is in the eastern portion of the state. It includes all of St. Louis City and much of northern St. Louis County, including the cities of Maryland Heights, University City, Ferguson and Florissant. With a Cook Partisan Voting Index rating of D+29, it is the most Democratic U.S. Congressional district in Missouri and is tied with Colorado's 1st congressional district as the 16th most Democratic nationwide. Roughly half of the district's population is African American.

Its current representative is Democrat Wesley Bell, the former St. Louis County district attorney. Bell was first elected in 2024 after defeating two-term congresswoman Cori Bush. Bush herself had toppled ten-term incumbent William Lacy Clay, Jr., who had previously represented the district between 2001 and 2021, succeeding his father, William Lacy Clay, Sr.