M protein (Streptococcus)

Not to be confused with Protein M.
Gram_pos_anchor
Identifiers
SymbolGram_pos_anchor
PfamPF00746
Pfam clanCL0501
InterProIPR019948
PROSITEPDOC00373
Available protein structures:
PDB  IPR019948 PF00746 (ECOD; PDBsum)  
AlphaFold

M protein is a virulence factor that is produced by certain species of Streptococcus. The protein plays an important role in adhesion to and colonization of host tissues and especially in evading phagocytosis by immune cells.

The protein was originally identified by Rebecca Lancefield, who also formulated the Lancefield classification system for streptococcal bacteria.

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