MMP14

Mmp14
Identifiers
Aliases	Mt1-mmpmatrix metallopeptidase 14
External IDs	MGI: 101900; HomoloGene: 21040; GeneCards: [1]; OMA:- orthologs
Gene location (Human)
Chr.	Chromosome 15 (human)
End	27,899,864 bp
Gene location (Mouse)
Chr.	Chromosome 14 (mouse)
End	54,682,821 bp
RNA expression pattern
	Top expressed in
	ovary; ; esophagus; ; liver; ; quadriceps femoris muscle; ; stomach; ; colon; ; jejunum; ; ileum; ; duodenum; ; lung;
	Top expressed in
	calvaria; ; body of femur; ; umbilical cord; ; molar; ; stroma of bone marrow; ; external carotid artery; ; uterus; ; internal carotid artery; ; endothelial cell of lymphatic vessel; ; lip;
	More reference expression data
	n/a
Gene ontology
Molecular function	endopeptidase activity; metalloendopeptidase activity; integrin binding; protein binding; peptidase activity; metallopeptidase activity; zinc ion binding; hydrolase activity; metal ion binding; metalloaminopeptidase activity;
Cellular component	extracellular space; nucleus; cytoplasm; cytosol; plasma membrane; membrane; integral component of membrane; extracellular matrix; cytoplasmic vesicle; melanosome; macropinosome; intermediate filament cytoskeleton;
Biological process	ossification; angiogenesis; ovarian follicle development; response to hypoxia; endothelial cell proliferation; endochondral ossification; proteolysis; response to oxidative stress; male gonad development; response to mechanical stimulus; response to hormone; positive regulation of myotube differentiation; positive regulation of protein processing; response to organic cyclic compound; cell migration; positive regulation of cell growth; lung development; positive regulation of cell migration; collagen catabolic process; zymogen activation; endodermal cell differentiation; chondrocyte proliferation; astrocyte cell migration; response to estrogen; positive regulation of B cell differentiation; negative regulation of Notch signaling pathway; embryonic cranial skeleton morphogenesis; branching morphogenesis of an epithelial tube; tissue remodeling; negative regulation of focal adhesion assembly; head development; bone development; craniofacial suture morphogenesis; regulation of protein localization to plasma membrane; positive regulation of macrophage migration; response to odorant; skeletal system development; extracellular matrix organization;
	Sources:Amigo / QuickGO
Orthologs
	81707
	17387
	ENSRNOG00000010947
	ENSMUSG00000000957
	Q10739
	P53690
	NM_031056
	NM_008608
	NP_112318
	NP_032634
	Wikidata
View/Edit Human	View/Edit Mouse

Matrix metalloproteinase-14 is an enzyme that in humans is encoded by the MMP14 gene.