MIS18BP1

MIS18BP1
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1WGX
Identifiers
Aliases	MIS18BP1, C14orf106, HSA242977, KNL2, M18BP1, MIS18 binding protein 1
External IDs	OMIM: 618139; MGI: 2145099; HomoloGene: 10147; GeneCards: MIS18BP1; OMA:MIS18BP1 - orthologs
Gene location (Human)
Chr.	Chromosome 14 (human)
End	45,253,540 bp
Gene location (Mouse)
Chr.	Chromosome 12 (mouse)
End	65,219,378 bp
RNA expression pattern
	Top expressed in
	monocyte; ; ventricular zone; ; testicle; ; epithelium of colon; ; tendon of biceps brachii; ; gonad; ; ganglionic eminence; ; buccal mucosa cell; ; Achilles tendon; ; rectum;
	Top expressed in
	genital tubercle; ; tail of embryo; ; abdominal wall; ; zygote; ; medial ganglionic eminence; ; primitive streak; ; maxillary prominence; ; renal corpuscle; ; oocyte; ; mandibular prominence;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	DNA binding; protein binding; DNA-binding transcription factor activity, RNA polymerase II-specific;
Cellular component	chromosome; chromosome, centromeric region; nucleus; nucleoplasm;
Biological process	cell division; cell cycle; CENP-A containing chromatin assembly; regulation of transcription by RNA polymerase II;
	Sources:Amigo / QuickGO
Orthologs
	55320
	217653
	ENSG00000129534
	ENSMUSG00000047534
	Q6P0N0
	Q80WQ8
	NM_018353
	NM_172578
	NP_060823
	NP_766166
	Wikidata
View/Edit Human	View/Edit Mouse

MIS18 binding protein 1 is a protein that in humans is encoded by the MIS18BP1 gene. The gene is also known as LKNL2, M18BP1, C14orf106, and HSA242977. M18BP1 protein is an important component in the CENPA deposition pathway, and in most eukaryotes M18BP1 is necessary for chromosome segregation.