MED4

Available protein structures:
PDB	IPR019258 PF10018 (ECOD; PDBsum)
AlphaFold	IPR019258; PF10018;

Med4
Med4
Identifiers
Symbol	Med4
Pfam	PF10018
InterPro	IPR019258
PDB
Available protein structures:
PDB	IPR019258 PF10018 (ECOD; PDBsum)
AlphaFold	IPR019258; PF10018;

MED4
Identifiers
Aliases	MED4, ARC36, DRIP36, HSPC126, TRAP36, VDRIP, mediator complex subunit 4
External IDs	OMIM: 605718; MGI: 1914631; HomoloGene: 8568; GeneCards: MED4; OMA:MED4 - orthologs
Gene location (Human)
Chr.	Chromosome 13 (human)
End	48,095,131 bp
Gene location (Mouse)
Chr.	Chromosome 14 (mouse)
End	73,756,289 bp
RNA expression pattern
	Top expressed in
	gonad; ; gingival epithelium; ; palpebral conjunctiva; ; germinal epithelium; ; rectum; ; monocyte; ; epithelium of nasopharynx; ; testicle; ; right testis; ; tibial arteries;
	Top expressed in
	primary oocyte; ; interventricular septum; ; morula; ; ventricular zone; ; embryo; ; embryo; ; epiblast; ; abdominal wall; ; primitive streak; ; medial ganglionic eminence;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	thyroid hormone receptor binding; protein binding; transcription coregulator activity; nuclear receptor coactivator activity; vitamin D receptor binding; signaling receptor activity;
Cellular component	core mediator complex; membrane; nucleus; mediator complex; nucleoplasm;
Biological process	regulation of transcription by RNA polymerase II; positive regulation of transcription, DNA-templated; androgen receptor signaling pathway; intracellular steroid hormone receptor signaling pathway; regulation of transcription, DNA-templated; transcription by RNA polymerase II; transcription, DNA-templated; transcription initiation from RNA polymerase II promoter;
	Sources:Amigo / QuickGO
Orthologs
	29079
	67381
	ENSG00000136146
	ENSMUSG00000022109
	Q9NPJ6
	Q9CQA5
	NM_014166; NM_001270629
	NM_026119
	NP_001257558; NP_054885
	NP_080395
	Wikidata
View/Edit Human	View/Edit Mouse

Mediator of RNA polymerase II transcription subunit 4 also known as mediator complex subunit 4 (MED4), a component of Mediator or vitamin D3 receptor-interacting protein complex 36 kDa component (DRIP36) is a protein that in humans is encoded by the MED4 gene.