MDM4

MDM4
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2CR8, 2VJE, 2VJF, 2VYR, 3DAB, 3EQY, 3FDO, 3FE7, 3FEA, 3JZO, 3JZP, 3JZQ, 3LBJ, 3MQR, 3U15, 4RXZ, 2MWY, 2N06, 2N0W, 2N14, 2N0U
Identifiers
Aliases	MDM4, HDMX, MDMX, MRP1, p53 regulator, MDM4 regulator of p53, BMFS6
External IDs	OMIM: 602704; MGI: 107934; HomoloGene: 1794; GeneCards: MDM4; OMA:MDM4 - orthologs
Gene location (Human)
Chr.	Chromosome 1 (human)
End	204,558,120 bp
Gene location (Mouse)
Chr.	Chromosome 1 (mouse)
End	132,958,299 bp
RNA expression pattern
	Top expressed in
	nipple; ; oocyte; ; epithelium of colon; ; trabecular bone; ; skin of thigh; ; pylorus; ; Achilles tendon; ; sural nerve; ; cardia; ; pericardium;
	Top expressed in
	secondary oocyte; ; primary oocyte; ; zygote; ; genital tubercle; ; saccule; ; tail of embryo; ; granulocyte; ; neural layer of retina; ; otic placode; ; spermatocyte;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	enzyme binding; protein binding; metal ion binding; ubiquitin protein ligase activity; zinc ion binding;
Cellular component	nucleus; nucleoplasm;
Biological process	G0 to G1 transition; DNA damage response, signal transduction by p53 class mediator; protein stabilization; cell population proliferation; negative regulation of apoptotic process; negative regulation of transcription by RNA polymerase II; cellular response to hypoxia; negative regulation of protein catabolic process; negative regulation of cell population proliferation; protein ubiquitination; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; regulation of signal transduction by p53 class mediator; protein deubiquitination; protein-containing complex assembly; heart valve development; atrioventricular valve morphogenesis; endocardial cushion morphogenesis; ventricular septum development; atrial septum development;
	Sources:Amigo / QuickGO
Orthologs
	4194
	17248
	ENSG00000198625
	ENSMUSG00000054387
	O15151; Q5T0Y2
	O35618
NM_001204171; NM_001204172; NM_001278516; NM_001278517; NM_001278518;
	NM_001278519; NM_002393
	NM_008575; NM_001302801; NM_001302802; NM_001302803; NM_001302804
NP_001191100; NP_001191101; NP_001265445; NP_001265446; NP_001265447;
	NP_001265448; NP_002384
	NP_001289730; NP_001289731; NP_001289732; NP_001289733; NP_032601
	Wikidata
View/Edit Human	View/Edit Mouse

Protein Mdm4 is a protein that in humans is encoded by the MDM4 gene.