List of 500cc/MotoGP race winners

Grand Prix motorcycle racing is the premier championship of motorcycle road racing, which has been divided into three classes: MotoGP, Moto2, and Moto3. Former classes that have been discontinued include 350cc, 250cc, 125cc, 50cc/80cc, MotoE, and Sidecar. The premier class is MotoGP, which was formerly known as the 500cc class. The Grand Prix Road-Racing World Championship was established in 1949 by the sport's governing body the Fédération Internationale de Motocyclisme (FIM), and is the oldest motorsport world championship in existence. The motorcycles used in MotoGP are purpose-built for the sport, are unavailable for purchase by the general public and cannot be legally ridden on public roads.

Valentino Rossi holds the record for the most race wins in the premier class with 89. Marc Márquez is second with 73 wins, and Giacomo Agostini is third with 68 wins. Dani Pedrosa holds the record for most career wins without winning the championship with 31.