Limulus clotting factor B

Limulus clotting factor B
Identifiers
EC no.3.4.21.85
CAS no.848851-53-6
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
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PMCarticles
PubMedarticles
NCBIproteins

Limulus clotting factor B (EC 3.4.21.85) is an enzyme. This enzyme catalyses the following chemical reaction:

Selective cleavage of -Arg98-Ile99- bond in limulus proclotting enzyme to form active clotting enzyme

This enzyme is present in the hemocyte granules of the horseshoe crabs Limulus and Tachypleus. In the immunity-related clotting pathways of these organisms, factor B is downstream of Limulus clotting factor C, but upstream of Limulus clotting enzyme.