Lee County, Mississippi

County of Lee
Clock tower of the Lee County Courthouse
Location within the U.S. state of Mississippi
Country United States
State Mississippi
FoundedOctober 26, 1866 (1866-10-26)
Named afterGen. Robert E. Lee
SeatTupelo
Largest cityTupelo
Area
 • Total
453 sq mi (1,170 km2)
 • Land450 sq mi (1,200 km2)
 • Water3.2 sq mi (8.3 km2)  0.7%
Population
 (2020)
 • Total
83,343
 • Estimate 
(2024)
83,012
 • Density190/sq mi (72/km2)
Time zoneUTC−6 (Central)
 • Summer (DST)UTC−5 (CDT)
ZIP Codes
38801, 38804, 38824, 38826, 38828, 38843, 38849, 38857, 38858, 38860, 38862, 38866, 38868, 38879
Area code662
Congressional district1st
Websiteleecoms.com

Lee County is a county in U.S. state of Mississippi. At the 2020 census, the population was 83,343. Its county seat is Tupelo. Lee County is included in the Tupelo Micropolitan Statistical Area.