Laser Doppler imaging

This article is about perfusion imaging. For the point technique, see Laser Doppler flowmetry.
Laser Doppler imaging
Example of flow-contrast microangiography in the optic disc region of the human retina, rendered computationally from Doppler-sensitive optical fluctuations (camera-based implementation; see § Digital holography / laser Doppler holography).
SynonymsLaser Doppler perfusion imaging (LDPI); Laser Doppler perfusion imaging (LDI)
PurposeMap microvascular perfusion (blood-flow–related signal) non-invasively
Test ofMicrocirculation / perfusion
Based onLaser Doppler flowmetry, dynamic light scattering, coherent speckle fluctuation analysis; (in some implementations) digital holography

Laser Doppler imaging (LDI), also called laser Doppler perfusion imaging (LDPI), is a non-contact optical technique for mapping signals related to microvascular blood perfusion in tissue. It illuminates tissue with coherent laser light and analyzes temporal fluctuations in the backscattered light caused by scattering from moving red blood cells; these fluctuations contain Doppler-broadened frequency components. LDI typically reports a perfusion-related index (often in arbitrary perfusion units) proportional to the amount of moving blood cells and their velocities within the sampled volume, rather than a direct absolute volumetric flow rate.

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