LY-344864

LY-344864
Clinical data
Other names	LY344864; LY-344,864
Identifiers
	IUPAC name N-[(6R)-6-(dimethylamino)-6,7,8,9-tetrahydro-5H-carbazol-3-yl]-4-fluorobenzamide;
CAS Number	186544-26-3;
PubChem CID	5311097;
IUPHAR/BPS	21;
ChemSpider	4470627;
UNII	L4WN6HH63L;
ChEBI	CHEBI:93683;
ChEMBL	ChEMBL1628565;
CompTox Dashboard (EPA)	DTXSID201134040 ;
Chemical and physical data
Formula	C21H22FN3O
Molar mass	351.425 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES CN(C)[C@@H]1CCC2=C(C1)C3=C(N2)C=CC(=C3)NC(=O)C4=CC=C(C=C4)F;
	InChI InChI=1S/C21H22FN3O/c1-25(2)16-8-10-20-18(12-16)17-11-15(7-9-19(17)24-20)23-21(26)13-3-5-14(22)6-4-13/h3-7,9,11,16,24H,8,10,12H2,1-2H3,(H,23,26)/t16-/m1/s1; Key:GKWHICIUSVVNGX-MRXNPFEDSA-N;

LY-344864 is an experimental drug of the triptan and tetrahydrocarbazolamine families with a tricyclic cyclized tryptamine structure which acts as an agonist for the 5-HT_1F serotonin receptor. It has antimigraine activity in animal models but was never developed for this indication as a medicine, however it continues to be used in scientific research and in recent years has been investigated as a potential agent for stimulating mitochondrial biogenesis, which can facilitate repair to damaged cells and tissues with a number of potential medical applications.