LONP1

LONP1
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2X36
Identifiers
Aliases	LONP1, LON, LONP, LonHS, PIM1, PRSS15, hLON, CODASS, lon peptidase 1, mitochondrial, Lon protease homolog, mitochondrial
External IDs	OMIM: 605490; MGI: 1921392; HomoloGene: 3521; GeneCards: LONP1; OMA:LONP1 - orthologs
EC number	3.4.21.53
Gene location (Human)
Chr.	Chromosome 19 (human)
End	5,720,572 bp
Gene location (Mouse)
Chr.	Chromosome 17 (mouse)
End	56,933,887 bp
RNA expression pattern
	Top expressed in
	right adrenal gland; ; right adrenal cortex; ; left adrenal gland; ; left adrenal cortex; ; apex of heart; ; stromal cell of endometrium; ; left ventricle; ; anterior pituitary; ; right lobe of liver; ; muscle of thigh;
	Top expressed in
	adrenal medulla; ; Ileal epithelium; ; right kidney; ; muscle of thigh; ; primitive streak; ; right ventricle; ; proximal tubule; ; brown adipose tissue; ; left lobe of liver; ; epiblast;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	nucleotide binding; DNA binding; mitochondrial promoter sequence-specific DNA binding; ADP binding; DNA polymerase binding; G-quadruplex DNA binding; peptidase activity; ATPase activity; protein binding; single-stranded RNA binding; serine-type peptidase activity; serine-type endopeptidase activity; hydrolase activity; ATP binding; ATP-dependent peptidase activity; sequence-specific DNA binding; single-stranded DNA binding;
Cellular component	membrane; nucleoplasm; mitochondrial matrix; mitochondrial nucleoid; nucleus; mitochondrion; cytosol;
Biological process	mitochondrial DNA metabolic process; mitochondrial genome maintenance; ageing; mitochondrion organization; proteolysis; protein catabolic process; response to aluminum ion; response to hormone; proteolysis involved in cellular protein catabolic process; protein homooligomerization; protein quality control for misfolded or incompletely synthesized proteins; response to hypoxia; cellular response to oxidative stress; oxidation-dependent protein catabolic process; chaperone-mediated protein complex assembly;
	Sources:Amigo / QuickGO
Orthologs
	9361
	74142
	ENSG00000196365
	ENSMUSG00000041168
	P36776
	Q8CGK3
	NM_001276479; NM_001276480; NM_004793
	NM_028782
	NP_001263408; NP_001263409; NP_004784
	NP_083058
	Wikidata
View/Edit Human	View/Edit Mouse

Lon protease homolog, mitochondrial is a protease, an enzyme that in humans is encoded by the LONP1 gene.