Ivonescimab
| Monoclonal antibody | |
|---|---|
| Type | ? |
| Source | Humanized (from hamster) |
| Target | PD-1, VEGF-A |
| Clinical data | |
| Other names | AK112 |
| Pharmacokinetic data | |
| Elimination half-life | 6-7 days |
| Identifiers | |
| CAS Number | |
| PubChem SID | |
| DrugBank | |
| UNII | |
Ivonescimab is a humanized bispecific monoclonal antibody currently being trialed for use against non-small-cell lung cancer. Developed by Akeso, it has been approved in China for the treatment of epidermal growth factor receptor-mutated locally advanced or metastatic non-squamous NSCLC in patients who have progressed past tyrosine kinase inhibitor therapy, and is undergoing clinical trials elsewhere.