Isomyosamine

Isomyosamine
Identifiers
CAS Number	53844-46-5;
3D model (JSmol)	Interactive image;
ChemSpider	9461533;
PubChem CID	11286546;
UNII	3A50Y1J4LP;
CompTox Dashboard (EPA)	DTXSID80461155 ;
	InChI InChI=1S/C9H10N2/c1-3-8(7-10-5-1)9-4-2-6-11-9/h1,3,5-7,9H,2,4H2 Key: GXTVPHUMJMZDSF-UHFFFAOYSA-N;
	SMILES C1CC(N=C1)C2=CN=CC=C2;
Properties
Chemical formula	C9H10N2
Molar mass	146.193 g·mol−1
Related compounds
Related compounds	Myosmine; Nicotine
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). Infobox references

Isomyosamine, also known as MyMD-1 or MYMD-1, is a synthetic derivative of tobacco plant alkaloids being developed as a metabolic- and immunomodulator by MyMD Pharmaceuticals. To date, isomyosamine has been shown to suppress the production of IFN-γ, IL-2, IL-10, and TNF-α, and decrease the severity of experimental thyroiditis in a murine model. Trials in humans are being planned, and some are underway, examining the potential benefits of isomyosamine in autoimmune diseases such as rheumatoid arthritis, and in sarcopenia and frailty.

MyMD Pharmaceuticals claim that MYMD-1 is not immunosuppressive, and thus should not be associated with the dangerous side effects such as infections that are seen in currently used TNF-α inhibitors such as adalimumab. While it is true that there currently is no evidence of immunosuppression in isomyosamine recipients, this has not yet been tested in large clinical trials.