Iso-LSD

Iso-LSD
Clinical data
Other namesIsoLSD; I-LSD; d-Iso-LSD; (+)-Iso-LSD; (5R-8S)-LSD; Isolysergic acid diethylamide; N,N-Diethylisolysergamide; iso-Lysergic acid diethylamide; N,N-Diethyl-6-methyl-9,10-didehydroergoline-8α-carboxamide; d-Isolysergic acid diethylamide
Routes of
administration
Oral
Drug classSerotonin receptor modulator
ATC code
  • None
Pharmacokinetic data
Elimination half-life12 hours
Identifiers
  • (6aR,9S)-N,N-diethyl-7-methyl-6,6a,8,9-tetrahydro-4H-indolo[4,3-fg]quinoline-9-carboxamide
CAS Number
PubChem CID
IUPHAR/BPS
ChemSpider
UNII
CompTox Dashboard (EPA)
ECHA InfoCard100.387.572
Chemical and physical data
FormulaC20H25N3O
Molar mass323.440 g·mol−1
3D model (JSmol)
  • CCN(CC)C(=O)[C@@H]1CN([C@@H]2CC3=CNC4=CC=CC(=C34)C2=C1)C
  • InChI=1S/C20H25N3O/c1-4-23(5-2)20(24)14-9-16-15-7-6-8-17-19(15)13(11-21-17)10-18(16)22(3)12-14/h6-9,11,14,18,21H,4-5,10,12H2,1-3H3/t14-,18+/m0/s1
  • Key:VAYOSLLFUXYJDT-KBXCAEBGSA-N

Iso-LSD, also known as d-iso-LSD, (+)-iso-LSD, or (5R-8S)-LSD, as well as N,N-diethylisolysergamide, is a serotonin receptor modulator of the lysergamide family related to lysergic acid diethylamide (LSD). It is the 8-position epimer of LSD, with iso-LSD being 8α (8S) and LSD being 8β (8R). Iso-LSD is also the N,N-diethyl derivative of isoergine (isolysergic acid amide; iso-LSA), a constituent found in morning glory seeds. Iso-LSD is one of four possible stereoisomers of LSD.