Infected cell protein 47

US12
Identifiers
SymbolHerpes_US12
PfamPF05363
InterProIPR008026
CATH5U1D
SCOP21qlo / SCOPe / SUPFAM
Available protein structures:
PDB  IPR008026 PF05363 (ECOD; PDBsum)  
AlphaFold

Infected cell protein 47 also ICP-47 or ICP47 is a protein encoded by the viruses such as Herpes simplex virus and Cytomegalovirus that allows them to evade the human immune system's CD8 T-cell response by interfering with an infected cell's ability to show viral epitopes to T cells. Its secondary structure shows three helices.