Hilbert's eighth problem

Hilbert's eighth problem is one of David Hilbert's list of open mathematical problems posed in 1900. It concerns various branches of number theory, and is actually a set of three different problems:

Along with Hilbert's sixteenth problem, it became one of the hardest problems on the list, with very few particular results towards its solution. After a century, the Riemann hypothesis was listed as one of Smale's problems and the Millennium Prize Problems. The twin prime conjecture and Goldbach conjecture being special cases of linear diophantine equations became two of four Landau problems.