Hexestrol dipropionate

Hexestrol dipropionate
Clinical data
Other names	Hexestrol 4,4'-dipropionate
Identifiers
	IUPAC name [4-[4-(4-propanoyloxyphenyl)hexan-3-yl]phenyl] propanoate;
CAS Number	4825-53-0 ;
PubChem CID	107342;
ChemSpider	96605;
UNII	87WC4ICV8O;
ChEMBL	ChEMBL1577591;
CompTox Dashboard (EPA)	DTXSID40964036 ;
Chemical and physical data
Formula	C24H30O4
Molar mass	382.500 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES CCC(C1=CC=C(C=C1)OC(=O)CC)C(CC)C2=CC=C(C=C2)OC(=O)CC;
	InChI InChI=1S/C24H30O4/c1-5-21(17-9-13-19(14-10-17)27-23(25)7-3)22(6-2)18-11-15-20(16-12-18)28-24(26)8-4/h9-16,21-22H,5-8H2,1-4H3; Key:HZLYMVNJKHJFRO-UHFFFAOYSA-N;

Hexestrol dipropionate (brand name Hexanoestrol, Retalon Oleosum), or hexestrol dipropanoate, is a synthetic, nonsteroidal estrogen of the stilbestrol group related to diethylstilbestrol. It is an ester of hexestrol, and has been known since at least 1931. The drug has been used in the past to inhibit lactation in women.

Parenteral potencies and durations of nonsteroidal estrogens
Estrogen	Form	Major brand name(s)	EPD (14 days)	Duration
Diethylstilbestrol (DES)	Oil solution	Metestrol	20 mg	1 mg ≈ 2–3 days; 3 mg ≈ 3 days
Diethylstilbestrol dipropionate	Oil solution	Cyren B	12.5–15 mg	2.5 mg ≈ 5 days
Diethylstilbestrol dipropionate	Aqueous suspension	?	5 mg	? mg = 21–28 days
Dimestrol (DES dimethyl ether)	Oil solution	Depot-Cyren, Depot-Oestromon, Retalon Retard	20–40 mg	?
Fosfestrol (DES diphosphate)^a	Aqueous solution	Honvan	?	<1 day
Dienestrol diacetate	Aqueous suspension	Farmacyrol-Kristallsuspension	50 mg	?
Hexestrol dipropionate	Oil solution	Hormoestrol, Retalon Oleosum	25 mg	?
Hexestrol diphosphate^a	Aqueous solution	Cytostesin, Pharmestrin, Retalon Aquosum	?	Very short
Note: All by intramuscular injection unless otherwise noted. Footnotes: ^a = By intravenous injection. Sources: See template.