Heat shock factor

HSF-type DNA-binding
Structure of the dimeric DNA binding domain of the yeast heat shock factor (cyan and green) bound to DNA (brown) based on PDB: 3HTS​.
Identifiers
SymbolHSF_DNA-bind
PfamPF00447
InterProIPR000232
PROSITEPDOC00381
SCOP21hks / SCOPe / SUPFAM
Available protein structures:
PDB  1FBQ​, 1FBS​, 1FBU​, 1FYK​, 1FYL​, 1FYM​, 1HKS​, 1HKT​, 2HTS​, 3HSF​, 3HTSIPR000232 PF00447 (ECOD; PDBsum)  
AlphaFold
Vertebrate heat shock transcription factor
Identifiers
SymbolVert_HS_TF
PfamPF06546
InterProIPR010542
Available protein structures:
PDB  IPR010542 PF06546 (ECOD; PDBsum)  
AlphaFold

In molecular biology, heat shock factors (HSF), are the transcription factors that regulate the expression of the heat shock proteins. A typical example is the heat shock factor of Drosophila melanogaster.