Hailey–Hailey disease
| Hailey–Hailey disease | |
|---|---|
| Other names | Familial benign chronic pemphigus |
| Left axilla mild, uninfected Hailey–Hailey lesion | |
| Specialty | Medical genetics |
| Symptoms | Rashes and blisters on the skin, could be painful to the touch with a possibility of acantholysis, erythema and hyperkeratosis. |
| Usual onset | Late teenage years or 30s-40s |
| Duration | Chronic |
| Causes | Mutations in the ATP2C1 gene |
| Risk factors | Family history |
| Named after | Hugh Edward Hailey and William Howard Hailey |
Hailey–Hailey disease (HHD), or familial benign chronic pemphigus or familial benign pemphigus, was originally described by the Hailey brothers (Hugh Edward and William Howard) in 1939. It is a genetic disorder that causes blisters to form on the skin.