HSP90AB1

HSP90AB1
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1QZ2, 1UYM, 2L6J, 3FWV, 3NMQ, 3PRY, 3UQ3, 5FWL, 5FWM, 5FWK
Identifiers
Aliases	HSP90AB1, D6S182, HSP84, HSP90B, HSPC2, HSPCB, heat shock protein 90kDa alpha family class B member 1, heat shock protein 90 alpha family class B member 1
External IDs	OMIM: 140572; MGI: 96247; HomoloGene: 74306; GeneCards: HSP90AB1; OMA:HSP90AB1 - orthologs
Gene location (Human)
Chr.	Chromosome 6 (human)
End	44,253,888 bp
Gene location (Mouse)
Chr.	Chromosome 17 (mouse)
End	45,884,197 bp
RNA expression pattern
	Top expressed in
	frontal pole; ; Brodmann area 10; ; paraflocculus of cerebellum; ; lateral nuclear group of thalamus; ; middle frontal gyrus; ; pars compacta; ; pons; ; tibialis anterior muscle; ; pars reticulata; ; spinal ganglia;
	Top expressed in
	mandibular prominence; ; Gonadal ridge; ; maxillary prominence; ; epiblast; ; tail of embryo; ; primitive streak; ; gastrula; ; subiculum; ; hand; ; habenula;
	More reference expression data
	n/a
Gene ontology
Molecular function	nucleotide binding; transmembrane transporter binding; unfolded protein binding; GTP binding; histone deacetylase binding; UTP binding; nitric-oxide synthase regulator activity; kinase binding; MHC class II protein complex binding; protein kinase regulator activity; CTP binding; dATP binding; double-stranded RNA binding; TPR domain binding; sulfonylurea receptor binding; protein kinase binding; RNA binding; ATP binding; heat shock protein binding; peptide binding; protein homodimerization activity; ATP-dependent protein binding; cadherin binding; protein dimerization activity; DNA polymerase binding; disordered domain specific binding; histone methyltransferase binding; protein binding; identical protein binding; ubiquitin protein ligase binding; tau protein binding;
Cellular component	cytoplasm; melanosome; intracellular anatomical structure; nucleoplasm; cell surface; brush border membrane; basolateral plasma membrane; apical plasma membrane; mitochondrion; inclusion body; COP9 signalosome; extracellular exosome; ooplasm; sperm head plasma membrane; lysosomal membrane; extracellular region; nucleus; cytosol; plasma membrane; membrane; aryl hydrocarbon receptor complex; secretory granule lumen; ficolin-1-rich granule lumen; protein-containing complex; soma; dendritic growth cone; axonal growth cone; perinuclear region of cytoplasm; HSP90-CDC37 chaperone complex;
Biological process	negative regulation of neuron apoptotic process; cellular response to interleukin-4; response to salt stress; Fc-gamma receptor signaling pathway involved in phagocytosis; placenta development; positive regulation of nitric oxide biosynthetic process; regulation of protein ubiquitination; cellular response to organic cyclic compound; response to stress; negative regulation of apoptotic process; response to organic substance; supramolecular fiber organization; positive regulation of protein serine/threonine kinase activity; response to unfolded protein; regulation of type I interferon-mediated signaling pathway; regulation of interferon-gamma-mediated signaling pathway; protein folding; positive regulation of cell size; regulation of cellular response to heat; positive regulation of protein binding; virion attachment to host cell; protein stabilization; positive regulation of phosphoprotein phosphatase activity; response to cocaine; negative regulation of complement-dependent cytotoxicity; xenobiotic metabolic process; telomere maintenance via telomerase; positive regulation of transforming growth factor beta receptor signaling pathway; negative regulation of proteasomal ubiquitin-dependent protein catabolic process; neutrophil degranulation; positive regulation of cell differentiation; chaperone-mediated protein complex assembly; positive regulation of telomerase activity; negative regulation of transforming growth factor beta activation; telomerase holoenzyme complex assembly; positive regulation of protein localization to cell surface; central nervous system neuron axonogenesis; establishment of cell polarity; positive regulation of peptidyl-serine phosphorylation; axon extension; negative regulation of protein metabolic process; positive regulation of protein kinase B signaling; negative regulation of proteasomal protein catabolic process; positive regulation of tau-protein kinase activity; positive regulation of cyclin-dependent protein kinase activity;
	Sources:Amigo / QuickGO
Orthologs
	3326
	15516
	ENSG00000096384
	ENSMUSG00000023944
	P08238; Q6PK50
	P11499
NM_001271969; NM_001271970; NM_001271971; NM_001271972; NM_007355;
	NM_001371238
	NM_008302
NP_001258898; NP_001258899; NP_001258900; NP_001258901; NP_031381;
	NP_001358167; NP_001258901.1
	NP_032328
	Wikidata
View/Edit Human	View/Edit Mouse

Heat shock protein HSP 90-beta also called HSP90beta is a protein that in humans is encoded by the HSP90AB1 gene.