HIV capsid inhibition

In the management of HIV/AIDS, HIV capsid inhibitors are antiretroviral medicines that target the capsid shell of the virus. This is in contrast to other antiretroviral drugs used to treat HIV, which do not directly target the viral capsid. Because of this, drugs that specifically inhibit the HIV capsid are being developed in order to reduce the replication of HIV and treat infections that have become resistant to other antiretroviral therapies. These have also been termed capsid-targeting antivirals, capsid effectors, and capsid assembly modulators (CAMs).

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