HEMGN

HEMGN
Identifiers
Aliases	HEMGN, CT155, EDAG, EDAG-1, NDR, hemogen
External IDs	OMIM: 610715; MGI: 2136910; HomoloGene: 14223; GeneCards: HEMGN; OMA:HEMGN - orthologs
Gene location (Human)
Chr.	Chromosome 9 (human)
End	97,944,856 bp
Gene location (Mouse)
Chr.	Chromosome 4 (mouse)
End	46,413,506 bp
RNA expression pattern
	Top expressed in
	trabecular bone; ; sperm; ; bone marrow; ; bone marrow cell; ; monocyte; ; right testis; ; left testis; ; blood; ; testicle; ; ganglionic eminence;
	Top expressed in
	fetal liver hematopoietic progenitor cell; ; tibiofemoral joint; ; human fetus; ; body of femur; ; spleen; ; right lobe of liver; ; blood; ; bone marrow; ; tail of embryo; ; yolk sac;
	More reference expression data
	n/a
Gene ontology
Molecular function	protein binding;
Cellular component	nucleus; nucleoplasm;
Biological process	multicellular organism development; cell differentiation; regulation of osteoblast differentiation;
	Sources:Amigo / QuickGO
Orthologs
	55363
	93966
	ENSG00000136929
	ENSMUSG00000028332
	Q9BXL5
	Q9ERZ0
	NM_018437; NM_197978
	NM_053149
	NP_060907; NP_932095
	NP_444379
	Wikidata
View/Edit Human	View/Edit Mouse

Hemogen is a protein that in humans is encoded by the HEMGN gene. It plays a crucial role in erythropoiesis, the process of red blood cell formation, by acting as a nuclear transcriptional regulator. Hemogen modulates gene expression involved in the proliferation, differentiation, and survival of erythroid progenitor cells, thereby contributing to the maintenance of normal red blood cell counts and responding to erythropoietic stress.