Guanidine
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| Names | |||
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| Preferred IUPAC name
Guanidine | |||
| Other names
Iminomethanediamine,
Carbamimidamide
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| Identifiers | |||
3D model (JSmol)
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| 506044 | |||
| ChEBI | |||
| ChEMBL | |||
| ChemSpider | |||
| DrugBank | |||
| ECHA InfoCard | 100.003.656 | ||
| EC Number |
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| 100679 | |||
| MeSH | Guanidine | ||
PubChem CID
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| UNII | |||
CompTox Dashboard (EPA)
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| Properties | |||
| CH5N3 | |||
| Molar mass | 59.072 g·mol−1 | ||
| Melting point | 50 °C (122 °F; 323 K) | ||
| 1840 mg/L | |||
| log P | −1.251 | ||
| Vapor pressure | 4.1 mmHg | ||
| Basicity (pKb) | 0.4 | ||
| Conjugate acid | Guanidinium | ||
| Thermochemistry | |||
Std enthalpy of
formation (ΔfH⦵298) |
−57 – −55 kJ mol−1 | ||
Std enthalpy of
combustion (ΔcH⦵298) |
−1.0511 – −1.0531 MJ mol−1 | ||
| Pharmacology | |||
| Pharmacokinetics: | |||
| 7–8 hours | |||
| Hazards | |||
| GHS labelling: | |||
| Danger | |||
| H225, H301, H302, H302+H332, H311, H314, H315, H319, H331, H332, H370 | |||
| P210, P233, P240, P241, P242, P243, P260, P262, P264, P264+P265, P270, P271, P280, P301+P316, P301+P317, P301+P330+P331, P302+P352, P302+P361+P354, P303+P361+P353, P304+P340, P305+P351+P338, P305+P354+P338, P308+P316, P316, P317, P321, P330, P332+P317, P337+P317, P361+P364, P362+P364, P363, P370+P378, P403+P233, P403+P235, P405, P501 | |||
| Lethal dose or concentration (LD, LC): | |||
LD50 (median dose)
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475 mg/kg (oral, rat) | ||
| Related compounds | |||
Related compounds
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Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references
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Guanidine is the compound with the formula HNC(NH2)2. It is a colourless solid that dissolves in polar solvents. It is a strong base that is used in the production of plastics and explosives. It is found in urine predominantly in patients experiencing renal failure. A guanidine moiety also appears in larger organic molecules, including on the side chain of arginine.